🦔➡️🚫[PTCH]➡️✅[SMO]➡️🧬[GLI]

#shh pathway mechanism #patched #ptch1 #smoothened #SMO #gli transcription factors #signal inhibition #gene activation #receptor signaling

🧬⚛️🔒/🔓

#chromatin remodeling #histone modification #dna methylation #gene silencing #gene activation #chemical biology #gene access